Police are hunting down an alleged killer after a young man was stabbed to death at a park in Brisbane's south.

Emergency services were called to a park on Mortimer Road in Acacia Ridge around 12.10am to find a man with multiple stab wounds to the abdomen.

Despite the efforts of paramedics, the 22-year-old victim died.

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The man has been identified as Bosco Minyurano.

His devastated family visited the park as police hunt down his alleged killer, who fled before authorities arrived.

A relative told 9News Minyurano was a nice and caring person who had a number of sporting achievements.

Detective Inspector Craig McDonald said Minyurano is believed to have known his alleged killer and said they were both part of a large group who had gathered at the park overnight.

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"It appears an altercation has taken place and a person has been stabbed," he said at a press conference.

"We have a number of people assisting detectives."

A witness told 9News there appeared to be six people in the group.

"There was alcohol on the scene, they were drinking," Taryn Loudon said.

"There's sort of been a bit of lead up to something."

9News understands police have identified a house of interest in their investigations. 

Anyone with information should contact Crime Stoppers on 1800 333 000.