A Melbourne tradie has been left with serious injuries to his face after being attacked by an e-scooter rider in a road rage incident.

Tyler Macaloney was driving home from his panel beating job in Parkville on Friday when he was confronted by a man who was weaving in and out of traffic.

The 22-year-old pulled up next to the rider and attempted to get him to ride in a separate bike lane for scooters.

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The rider reacted violently, attacking Macaloney.

"He sort of stepped into the view, and threw a punch through my window," Macaloney told 9News.

"I didn't expect it to go as aggressive as it did."

The e-scooter rider fled, leaving Macaloney with serious injuries to his nose.

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"My friend who was in the car when I got to my mum's place, I said, 'I need you to move my nose back into place, I cannot breathe!'" he told 9News.

"My nose has been detached and it's been fractured on the tip in three places."

Macaloney will undergo surgery in the coming days, with his face still badly bruised from the attack.

He will have to miss work for a number of weeks as he recovers from his injuries.

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"It 100 per cent could've been worse," he admitted.

"Anything could be worse.

"I could not be here right now, and my mum has to sort out a funeral."

The attacker still hasn't been found. He is believed to have been wearing a grey helmet and padded gloves.

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