Moderna moves closer to offering vaccine to 12- to 17-year-olds
Moderna announced on Tuesday that studies had found that its COVID-19 vaccine was 100 percent effective at stopping infection in adolescents aged 12 to 17.
The company intends to submit its data for the age group to global regulators, including the FDA, in early June.
The studies included 3,732 participants aged 12 to 17 and no cases of COVID-19 were found in any vaccinated participants. “No significant safety concerns” were identified.
The vaccine was 93 percent effective after the first dose and 100 percent effective after the second.
“We are encouraged that mRNA-1273 was highly effective at preventing COVID-19 in adolescents,” Moderna CEO Stéphane Bancel said in a statement. “It is particularly exciting to see that the Moderna COVID-19 vaccine can prevent SARS-CoV-2 infection.”
What this means: FDA’s emergency authorization for Moderna to be given to 12- to 17-year-olds would open up more opportunities for older students to get vaccinated before the next school year starts. The FDA has already granted emergency authorization for the Moderna vaccine to be given to those 18 and older and the Pfizer-BioNTech vaccine to be given to those 12 and older. Pfizer and its partner BioNTech received the emergency authorization for 12- to 15-year-olds about two weeks ago, after the FDA permitted it to be given to those 16 and older in December.
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Big Bucks Vaccine Lottereies Grow
States are increasingly turning to lotteries as a way to try to get hesitant people vaccinated against the coronavirus and boost lagging numbers.
New York and Maryland on Thursday announced that residents who get the COVID-19 vaccine will be eligible for prize money, with Oregon unveiling similar plans on Friday. All three states are following in the footsteps of Ohio, which launched a lottery-focused campaign earlier this month.
Health officials in the Buckeye State are already reporting some promising results: Vaccinations for people 16 and older increased 28 percent the weekend after the lottery announcement, compared to the previous weekend.
Dan Tierney, a spokesman for Ohio Gov. Mike DeWine (R), said vaccinations had been trending down before the lottery.
“Really the only thing that has changed was the availability of the Vax-a-Million incentive,” Tierney said.
Vaccinated residents in Ohio will be entered to win one of five $1 million prizes.
The approach is garnering interest in other parts of the country. About 10 other states have talked to DeWine or his staff about the lottery incentive, Tierney said.
The White House also gave its support to the idea on Friday.
“From the data we’ve seen, they appear to be working,” White House senior adviser for the COVID-19 response Andy Slavitt said during a press briefing.
“I think the reason they work is because the vast number of people who are not yet vaccinated are actually not opposed to getting vaccinated,” he added. “They’re just not prioritizing it very high. There are other things going on in their lives. Things that draw attention to it, like the lotteries in those states you mentioned, are, not surprisingly, very effective. And so we’re enthusiastic.”
Health officials are looking for new ways to spur people to get vaccinated, now that the most eager Americans have already received their shots. Nationally, vaccinations have fallen from over 3 million per day in April to about 1.8 million per day, according to Our World in Data.
Still, some experts cautioned that the lotteries are not a cure-all. While lotteries can prompt people who have not gotten around to getting a vaccine yet, they do not address underlying issues like concerns about safety or worries about taking time off work to get vaccinated.
“It doesn’t at all deal with the structural obstacles that might still be there,” said Micah Berman, associate professor of public health and law at The Ohio State University.
“It certainly creates a buzz. It just can’t be the only thing that the state does,” he added.
While there appears to be a short-term increase in vaccinations after the announcement, he noted, it is also unclear whether that will be sustained over the longer term.
“If someone is concerned about the safety of the vaccine, will a lottery push them over that tipping point such that they would get the vaccine? I think we’ll need to see,” said William Moss, executive director of the International Vaccine Access Center at Johns Hopkins University. “My guess right.
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US achieves full vaccinations for half of adults
CDC data showed the U.S. reached a huge milestone with its COVID-19 vaccination effort on Tuesday, with half of the nation’s adults being considered fully vaccinated.
Fifty percent, or more than 129 million, of Americans 18 and older are considered fully vaccinated.
A person is considered fully vaccinated in the U.S. two weeks after receiving their second dose of the Pfizer-BioNTech or Moderna vaccines or two weeks after receiving the only dose of the Johnson & Johnson vaccine.
What’s next: President Biden’s next target is to ensure that 70 percent of adults have received at least one dose of the vaccine by the Fourth of July. Tuesday’s data shows 61.6 percent of adults, amounting to more than 158 million, have received at least one dose.
The U.S. is also nearing half of its total population having received at least one dose of the vaccine, as Tuesday’s data shows 49.5 percent of Americans have reached this point.
But vaccinations have slowed in recent weeks after the most eager recipients received their vaccines, prompting states to institute incentives, including lotteries, to encourage unvaccinated people to get their shots.
CDC identifies only 10,000 COVID-19 infections in fully vaccinated, but likely an undercount
More than 10,000 fully vaccinated people in the U.S. have experienced a “breakthrough” COVID-19 infection, according to a new Centers for Disease Control and Prevention (CDC) study.
According to the CDC, a total of 10,262 vaccine breakthrough infections had been reported from 46 U.S. states and territories as of April 30, out of the approximately 101 million people who were fully vaccinated against COVID-19 at the time.
The agency noted, however, that the breakthrough number in the report is likely a substantial undercount.
State health departments voluntarily report vaccine breakthrough infections to the CDC, and people voluntarily report infections to states, so the data might not be complete or representative.
Many people with vaccine breakthrough infections, especially those who are asymptomatic or who experience mild illness, might not seek testing, CDC said.
Going forward, the CDC is limiting the monitoring of people who have been infected while vaccinated. The agency is only sequencing a limited number of the cases, which has drawn concern from scientists. CDC said only 5 percent of breakthrough cases were sequenced.
In addition, beginning May 1 the CDC shifted from monitoring all reported breakthroughs to only those that result in hospitalization or death. The agency said the narrowed focus means only the cases of “highest clinical and public health significance” get reported.
Why it matters: Tracking and sequencing help identify who might be more at risk, and whether certain variants can escape the vaccine’s neutralizing effects. Scientists have questioned the benefit of limiting surveillance, when casting a wider net would likely be more beneficial.
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Trump on Wuhan lab: Now everyone agrees ‘I was right’
Former President Trump on Tuesday took a victory lap for his assertion that the coronavirus originated in a lab in Wuhan, China, and defended using the term “Chinese virus,” which has been criticized as racist and blamed in part for a spike in violence against Asian Americans.
“Now everybody is agreeing that I was right when I very early on called Wuhan as the source of COVID-19, sometimes referred to as the China Virus,” Trump said in a statement.
Top U.S. public health officials and experts are increasingly lending credibility to the need for a deeper investigation into the origins of the coronavirus, but so far there is no definitive proof the virus leaked from a lab.
Experts and officials have also noted that even if the virus escaped from a lab, that doesn’t mean it was manufactured in one.
Still, Trump says he’s vindicated.
“To me it was obvious from the beginning but I was badly criticized, as usual. Now they are all saying ‘He was right.’ Thank you!” Trump added.
Keeps using that term: The World Health Organization last February urged people to avoid terms like the “Wuhan virus” or the “Chinese virus,” fearing it could spike a backlash against Asians.
Trump never followed that advice though, and researchers have found his tweets led to an increase in anti-Asian backlash. Last week, he was sued by a civil rights group for calling COVID-19 the “China virus.”