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UK Report: Booster Effectiveness Against Omicron Decreases Within 10 Weeks

The Hill

A United Kingdom Health Security Agency report published on Thursday suggests that the effectiveness of the COVID-19 booster against symptomatic infections of the omicron variant wanes within 10 weeks.

The report included 147,597 delta and 68,489 omicron cases, which were reported between Nov. 27 and Dec. 17. It analyzed the percentage of vaccine effectiveness between reported cases of the two strains in individuals who had received a two-dose regimen of the Astrazeneca, Pfizer or Moderna COVID-19 vaccine.

Researchers then compared the vaccine effectiveness of those who received a Pfizer or Moderna booster between reported cases of omicron and delta.

In all cases, data showed that the vaccines’ effectiveness against omicron was lower compared with their effectiveness against delta. The effectiveness of both the Moderna and Pfizer boosters was also found to decrease within weeks of people receiving the extra dose.

“Among those who received an AstraZeneca primary course, vaccine effectiveness was around 60% 2 to 4 weeks after either a Pfizer or Moderna booster, then dropped to 35% with a Pfizer booster and 45% with a Moderna booster by 10 weeks after the booster,” the report said.

Those percentages were a far cry from the vaccine effectiveness for individuals who had delta.

Vaccine effectiveness was between 80 and 100 percent in the first week for people who received either Pfizer or Moderna booster, and had only slightly dipped to just over 80 percent by the 10th week for those with the Pfizer booster.

In the 10th week, for individuals who received the Moderna booster and had delta, vaccine effectiveness was closer to 100 percent.

Researchers also compared the effectiveness of the Pfizer and Moderna boosters for individuals who received an initial two-dose regimen of the Pfizer vaccine.

“Among those who received a Pfizer primary course, vaccine effectiveness was around 70% after a Pfizer booster, dropping to 45% after 10-plus weeks and stayed around 70 to 75% after a Moderna booster up to 9 weeks after booster,” the report said of that data.

“These results should be interpreted with caution due to the low counts and the possible biases related to the populations with highest exposure to Omicron (including travellers and their close contacts) which cannot fully be accounted for,” the report noted.

The report also said, “There are insufficient severe cases of Omicron as yet to analyse vaccine effectiveness against hospitalisation, but this is expected to be better sustained, for both primary and booster doses.”

The CEO of Pfizer said earlier this month in an interview with CNBC that it was possible that people would need to receive a fourth dose of the COVID-19 vaccine in light of the omicron variant.

The post UK Report: Booster Effectiveness Against Omicron Decreases Within 10 Weeks appeared first on The St Kitts Nevis Observer.

UK, France with Record High Daily Covid Infections, FDA Okays 2nd Covid Pill, Ecuador Vax Mandate, World Stats

The UK set another daily Covid record on Thursday with 119,789 confirmed cases. There were a further 147 deaths within 28 days of a positive test.

It has also been a record-breaking week for booster and third jabs in the UK, with more than 968,665 administered on Wednesday, the highest number to date.

Prof Clare Bryant – a professor of immunology at the University of Cambridge – told BBC Radio 4’s Today programme that additional booster shots in the form of a fourth dose would be needed at some point, but exactly when was not yet clear.

“We are looking at fourth shots,” she said.

“I suspect it’s a question of when those will need to be introduced because of course a waning in immunity means that you may catch the virus a little bit more easily but don’t forget you’re still very well protected against severe disease and that’s absolutely critical.”

France on Thursday recorded its highest number of new COVID-19 cases since the pandemic began, as the country deals with a fifth wave of the virus.

More than 91,000 new coronavirus cases were confirmed in France on Thursday, according to Reuters.

“Today’s figures are not good,” said French Health Minister Olivier Véran. France will likely see 100,000 new daily cases soon, Varén warned earlier this week.

French health officials also recorded 179 new deaths and 61 COVID-19 hospitalizations in the intensive care unit due to COVID-19 on Thursday. Reuters noted that French President Emmanuel Macron is hoping to avoid enacting new restrictions and mandates, but the country’s government has said that all options would be considered.

Last week, French Prime Minister Jean Castex warned that the omicron variant was “spreading at lightning speed” throughout Europe and said the new strain will likely be dominant in France by early next year. Due to the rapid spread of the variant, France restricted travel from the U.K. last week, a move that the British government criticized as being not “effective or proportionate.”

Castex also said the government would be taking steps to address vaccine hesitancy, saying it was “not acceptable that the refusal of a few million French people to be vaccinated puts the life of an entire country at risk.”

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FDA authorizes Merck COVID-19 pill

 

© Getty Images

The Food and Drug Administration (FDA) on Thursday authorized a COVID-19 treatment from Merck, marking the second pill to become available to fight the virus.

This authorization is more limited than one on Wednesday for a Pfizer pill. The FDA authorized the Merck pill, developed with Ridgeback Biotherapeutics, for high-risk adults “for whom alternative COVID-19 treatment options authorized by the FDA are not accessible or clinically appropriate.”

That is, if other options are not available, the Merck pill can be used.

The drug is also only authorized for adults over the age of 18, as it “may affect bone and cartilage growth.”

There are also concerns that the Merck drug could cause birth defects if used during pregnancy, so the FDA said the drug is not recommended for use during pregnancy.

Antivirals are seen as potentially critical weapons in the fight against COVID-19, because they can be taken at home, without an IV or injection. But from the data, the benefit of molnupiravir appears very limited. In a clinical trial, a five-day course of the pill was shown to be only modestly effective– initially a 50 percent reduction in risk of hospitalization or death, but the company later revised it down to 30 percent. By comparison, Pfizer’s drug was 89 percent effective at reducing severe illness or death.

But the advantage over Pfizer’s drug, authorized on Wednesday, is in the numbers. The White House said Wednesday that 3 million courses of the Merck pill would be available in January, compared to 265,000 for Pfizer.

Testing challenge: Like the Pfizer pill, the Merck pill is also intended to be used within five days of symptoms beginning. That poses some logistical challenges, given that testing will need to be widely available enough that people can get their results back and seek the treatment from a health care provider within five days.

Read more here.

Antiviral may help at-risk, unvaccinated 

© Getty Images

A clinical trial has found that antiviral drug remdesivir reduces serious outcomes and hospitalization in unvaccinated high-risk COVID-19 patients, if administered in the early stages of their infection.

A three-day course of remdesivir cut hospitalization and death rates for COVID-19 by 87 percent.

Remdesivir, an infusion treatment manufactured by Gilead Sciences, was the first treatment ever to be authorized for use against the coronavirus in hospitalized patients.

The new study shows it can be effective on an outpatient basis as well.

A total of 562 patients took part in the study over an eight-month period.The double-blind, randomized, placebo-controlled trial was meant to evaluate the efficacy and safety of a three-day course of remdesivir in high-risk, non-hospitalized patients with COVID-19.

Key caveat: The findings are based on research that predates both delta variant and omicron.

Also unclear is how  well remdesivir would work early on in coronavirus patients who are vaccinated. The study focused on unvaccinated patients, the group most likely to become seriously ill or die if infected.

Remdesivir is an infusion drug, meaning it’s delivered intravenously. That could prove difficult to do outside a hospital, especially since treatment occurs over the course of three days.

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Ecuador makes COVID-19 vaccine mandatory for all eligible residents

The Ecuadorian government on Thursday issued a vaccine mandate for all eligible residents, making Ecuador the most recent country to issue this strict measure against the COVID-19 pandemic.

Exceptions to the far-reaching vaccine mandate will be made for people who cannot safely receive the vaccine, the government said. All other Ecuadorians ages five and above will be required to get the shot.

Ecuador’s Minister of Public Health Ximena Garzón cited the spread of new variants of concern, such as omicron, for the new requirement. To encourage vaccinations, 24-hour health centers will be kept open over the Christmas holiday, the health ministry said in the announcement.

The ministry stated that the country has enough vaccines in stock to immunize all its residents and stressed that the vaccines are considered to be safe and effective.

Roughly 77 percent of Ecuador’s population over the age of 5 is fully vaccinated against the coronavirus, Reuters reported. The news wire noted that the Ecuadorian government had said that it wanted to vaccinate 85 percent of its population this year.

Indonesia, Micronesia, Turkmenistan and Tajikistan have all issued similar vaccine mandates, and Germany and Austria are expected to do so next year.

The Ecuadorian health ministry said earlier this week that the delta variant of COVID-19 is still the most prevalent variant of concern in the country, though several cases of omicron have been confirmed.

According to the World Health Organization, Ecuador has so far confirmed more than 538,000 COVID-19 cases and over 33,000 related deaths since the beginning of the pandemic.

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WORLD STATS

Coronavirus Cases:

278,579,623

Deaths:

5,402,473

Recovered:

249,343,813
Highlighted in green
= all cases have recovered from the infection
Highlighted in grey
= all cases have had an outcome (there are no active cases)

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Latest News

December 24 (GMT)

Updates

  • 24,703 new cases and 998 new deaths in Russia [source]

The post UK, France with Record High Daily Covid Infections, FDA Okays 2nd Covid Pill, Ecuador Vax Mandate, World Stats appeared first on The St Kitts Nevis Observer.

Five-year-old boy fighting for life after being mauled by dog

A five-year-old boy is fighting for life in a Queensland hospital after being attacked by a dog.

The boy's family had been house sitting a property in Varsity Lakes on the Gold Coast when the owner's dog attacked him around midday on Christmas Eve, mauling the young child's back and neck.

He sustained life-threatening bites before going into cardiac arrest.

The boy's grandmother leapt into action, trying to pull the bull terrier cross american bulldog off the boy.

The grandmother is also in hospital but in a stable condition.

The boy was transported to Gold Coast University Hospital, where he underwent emergency surgery.

https://twitter.com/QldAmbulance/status/1474215149682585601

He remains there in a critical condition tonight.

Queensland Ambulance Service's Paul Young said multiple paramedics, including the aigh acuity response unit, attended the scene.

"They were house sitting a house, so it's not their dog and they were playing in the backyard and apparently the dog has just turned," Mr Young said.

How to track Santa's arrival in Australia

Having a survived the treacherous year that was 2021, Christmas is officially at our doorsteps.

Santa, too, is well on his way, making last minute preparations for his annual journey across the globe.

Children waiting anxiously in anticipation of the big man will be able to track his movements in just a matter of hours, as he treks across the world, departing from the North Pole.

READ MORE: What the weather will be like on Christmas Day

NORAD and other agenices across the globe will be tracking Santa this Christmas.

Deep in the Rocky Mountains, a special US military unit monitors the skies for weapons capable of destroying whole cities. But today, the North American Aerospace Defence Command (NORAD), takes on a different task – tracking Santa.

NORAD will give minute-by-minute updates as to where Santa's sleigh is around the world.

The website that shows where Santa is on his journey went live earlier this week.

The tracking allows eager and impatient kids to know when to expect Santa to come down their chimney – if they haven't already gone to bed.

While NORAD is seen as being on the cutting edge of new technology, the Santa tracker dates back generations.

The Santa tracker was first unveiled in 1955, when NORAD was known as the Continental Air Defence Command.

NORAD tracks Santa's progress across the globe each year.

At the time, the military had no interest in tracking where Santa Claus was.

But a telephone hotline allowing kids to speak to Santa just happened to be one digit off the Command's number. Consequently, they were deluged with calls asking about Santa.

READ MORE: Sydney couple's annual Christmas light display for charity

Ex-Cop Kim Potter Guilty in Fatal Shooting of Daunte Wright

The Hill

Kim Potter, the former Brooklyn Center, Minn., police officer who fatally shot 20-year-old Daunte Wright earlier this year after shouting “Taser,” on Thursday was found guilty of first- and second-degree manslaughter.

Judge Regina Chu required that Potter be taken into custody and held without bail. Potter’s sentencing date was set for Feb. 18.

In a press conference following the verdict, Minnesota Attorney General Keith Ellison (D) declined to give specifics regarding what sentence he would be calling for Potter to receive, only saying that he wanted “a fair one.”

“Accountability is not justice. Justice is restoration,” Ellison said. “Justice would be restoring Dante to life and making the Wright family whole again. Justice is beyond the reach that we have in this life for Daunte. But accountability is an important step, a critical, necessary step on the road to justice for us all.”

Officers said they pulled Wright over in April after noticing that he had been driving with an expired tag and an air freshener illegally hanging from his rearview mirror. Officers tried to arrest him after learning that there was a warrant out for his arrest regarding a misdemeanor weapons violation.

Wright reportedly struggled against officers who tried to get him out of the car. Potter could be heard saying “Taser” in body camera footage while brandishing her gun toward him. Potter could later be heard saying “I just shot him” after the 20-year-old drove away.

Shortly after the fatal shooting, Potter resigned from the Minnesota police department.

Potter took the witness stand last week, breaking down at one point and saying “I’m sorry” as she was being cross-examined by prosecutors.

She said she had made a mistake and had sought to use her stun gun against Wright instead of her gun. The defense team claimed that an officer could have been dragged by Wright’s car, saying Potter would have been within her rights to use such force.

A use-of-force expert testifying for the prosecution argued otherwise during the trial.

“The use of deadly force was not appropriate and the evidence suggests a reasonable officer in Officer Potter’s position could not have believed it was proportional to the threat at the time,” University of South Carolina School of Law professor Seth Stoughton said on the stand.

The trial was also emotional for the family of Wright, whose father reminisced about his son and noted their close relationship.

“He was me and my wife’s first child,” Arbuey Wright said during emotional testimony on Wednesday, USA Today reported.

“I miss him a lot. Every day.”

The post Ex-Cop Kim Potter Guilty in Fatal Shooting of Daunte Wright appeared first on The St Kitts Nevis Observer.

Prime Minister delivers Christmas message

In his annual Christmas message, Prime Minister Scott Morrison has encouraged everyone keep those who are doing it tough in their thoughts.

"There are six families in Devonport in northern Tasmania, from the Hillcrest Primary School this Christmas, who are completely devastated," Mr Morrison said.

"This Christmas we'll shed a tear and raise up prayers for them, I believe right across the country."

READ MORE: What the weather will be like on Christmas Day

Prime Minister Scott Morrison delivers his Christmas address for 2021.

Mr Morrison also acknowledged that while many Australians will be gathering for the first time in a while, many will also be alone this Christmas.

He said that the pandemic, especially the emergence of the Omicron variant, has continued to rattle the country.

"But together, always together and only together, do we keep pushing through," Mr Morrison said.

The Prime Minister also thanked Australians who are working around the Christmas period.

Scott Morrison

"They are driving trucks, delivering critical supplies, they're giving us our booster shots and doing our COVID tests."

Mr Morrison said no matter whatever the challenges, Christmas was a time of hope.

"Whatever comes our way, we back ourselves to overcome and to push through, as we have during the course of this pandemic, saving lives and livelihoods like few other countries in the world."

Watch the full message at the top of this story.

Hundreds forced to isolate after WA records five COVID-19 cases

Western Australia has recorded five new local cases of COVID-19, while venues have been restricted to only seated service, as authorities race to contain a COVID-19 outbreak.

Hundreds of people who went to a music event have been directed to go into isolation until January 3 after a positive case attended on Sunday morning.

Premier Mark McGowan yesterday announced new restrictions which will be in effect until at least 6am on Tuesday, December 28.

READ MORE: Mask rules return in NSW and Victoria

Some people in Perth are isolating after a potential COVID-19 exposure in Northbridge.

All nightclubs were ordered to close and masks were mandated indoors in Western Australia from 6pm yesterday.

Mr McGowan has today announced all licensed hospitality venues will only be allowed to provide seated service.

He said the restriction would allow Christmas lunches and dinners, but would impact service at pubs and bars.

The case which sparked the outbreak was an unvaccinated 25-year-old backpacker who travelled into the state from Queensland 12 days ago, and is originally from France.

Mr McGowan said advice from the Australian Border Force was that the man arrived in Australia before the onset of the pandemic, on January 7, 2020.

Mr McGowan said the man entered WA on December 12, before it was mandatory to be fully vaccinated against COVID-19 to enter the state.

"At the time, Queensland was set as a very low-risk jurisdiction as they had virtually no COVID in that state which meant people entering WA from Queensland were not required to be vaccinated at that point in time."

Mr McGowan said the five new cases today, of which at least two were not vaccinated, had been recorded as of 9am after 10,267 tests were taken yesterday.

He said more positives cases were expected to be discovered.

The new cases include a close contact of the backpacker, who also attended the Mess Hall event on Sunday, December 19.

The other three cases are casual contacts of backpacker who also attended the event and did not know the backpacker.

The fifth was announce mid-way through the premier's COVID-19 update and no other details are known.

Mr McGowan said anyone who attended the event had to get tested and self-quarantine until January 3.

WA Police have locked down the Fremantle Old Fire Station Hostel, where about 100 of 400 attendees at the event have been staying.

Mr McGowan said the hostel was not suitable to quarantine in so the attendees would all be provided with more suitable accommodation.

A number of new exposure sites across Perth have been published on WA.gov.au.

WA changes its classifications for entry from Queensland and South Australia

Mr McGowan has this afternoon announced that Queensland and South Australia will be declared 'high risk' zones as of 12.01am on Christmas Day due to their escalating COVID-19 situations.

https://twitter.com/MarkMcGowanMP/status/1474257185089622017

Under the 'high risk' setting, travel to WA from Queensland or SA will be limited to approved travellers only.

He has taken to social media to urge all Western Australians in Queensland or SA to "come home now".

Plans ruined as flights cancelled, COVID-19 test results not returned

Many Christmas plans have been ruined or are in limbo after a number of flights were cancelled due to crew members being forced into COVID-19 isolation.

The Melbourne and Sydney route has been worst hit, with around a dozen Virgin flights and around 10 Jetstar flights cancelled.

Around 20 planned flights to Queensland, South Australia and Tasmania have also not taken off.

READ MORE: Booster shots to be brought forward following ATAGI advice

Jetstar A320

Passengers took to social media to lash out at the airlines, claiming they had been left in the dark.

"I feel like screaming," one Twitter user wrote.

"Daughter in Sydney did all the right things. Double vacc, boostered, PCR test, Qld border pass. Jetstar just cancelled her flight to Bris. No explanation."

In a statement, Jetstar said a "large number" of their frontline workers were having to test and isolate as COVID-19 close contacts in Sydney and Melbourne, forcing some "late adjustments".

"We appreciate the frustration this causes, especially as customers are travelling for Christmas, and sincerely apologise for the impact these changes are having on travel plans," the statement read.

READ MORE: NSW records 5612 COVID-19 cases, one death, as masks return

"We are working to minimise any delays and re-accommodating passengers on flights as close as possible to their original departure times across both Jetstar and Qantas services."

Virgin Australia is also reported to have made some changes to its schedule.

Both airlines told 9News that they contacted all passengers yesterday and last night at the latest, and they are getting them on free replacement flights today.

Qantas has cancelled a small number of flights, but it is understood this was due to lack of demand.

Other travellers have been left stranded at the airport after failing to get their COVID-19 tests returned in time.

A woman has told 9News she had been tested on Wednesday morning but was left without results and unable to board her flight today.