Police have launched an investigation into the death of a man found with a stab wound in Rockhampton.

Emergency services were initially called to the Cypress Avenue, Norman Gardens address just after midday yesterday following reports of an assault. 

A 51-year-old man was found at the scene having sustained a single stab wound to his chest.

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He was taken to Rockhampton Hospital, where he later died.

A 48-year-old woman, also from Norman Gardens, is assisting police with their investigations and a crime scene was declared at the address. 

Detective Inspector Darrin Shadlow said the death was being treated as a "domestic incident" and suspicious.

"We'll continue to speak to further people … as well as the 48-year-old woman, but we're still conducting our investigations." Inspector Shadlow said. 

Detectives are encouraging anyone with information to come forward and speak with police.