A 58-year-old woman has died after falling at least 50 metres from a Far North Queensland waterfall.

Police said one of the Cairns woman's fellow walkers called emergency services after she fell from the top of Windin Falls about 1pm.

A rescue helicopter, police on foot and drones were called in to help search for the woman but she couldn't be found until about 4pm.

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According to Tourism Tropical North Queensland the falls are a roughly 90-minute walk along the Old Cairns Track, in the Wooroonooran National Park.

"Exercise extreme caution and stay back from the edges," the website warns.

"There is a natural infinity pool at the top of the falls that drops deep into the valley below."

A police spokesman said varying reports indicated the waterfall was about 50 to 100 metres high.

Police have notified the woman's next of kin and will prepare a report for the coroner.