A NSW bus driver has been charged after allegedly letting a 16-year-old member of the public drive his bus.

Police officers from Campsie, in Sydney's south-west, launched an investigation after receiving reports the bus driver was letting the teenager operate his vehicle while there were passengers on board.

The bus driver allegedly let the teenager operate the bus numerous times between March 10 and March 27, according to police.

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Officers then visited a home in Menai, in southern Sydney, at around 2pm yesterday where they arrested the 25-year-old bus driver.

He was taken to Sutherland Police station and charged with negligently moving or driving a vehicle and subjecting persons to risk.

He has been given conditional bail and is set to appear at Sutherland Local Court on April 28.

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Transit Systems, the company the 25-year-old driver works for in Sydney's Inner West, issued a statement on the incident.

"The driver has been stood down while NSW Police complete their investigation," the statement said.

"We are unable to provide any further updates on the matter given it is police investigation.

"We will continue to cooperate with the relevant authorities."