A 33-year-old man has been charged with murder after police discovered the body of his 61-year-old mother in Perth's south last night.

Emergency services were called to the home on Gallipoli Avenue in Byford about 7.05pm after receiving reports of a woman injured.

9News understands the man was seen leaving the house in a silver Peugeot station sedan.

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Police said officers spotted the car travelling north on Great Northern Highway, north of Bindoon, about 9.15pm.

"Officers activated emergency lights and sirens, however the driver failed to stop and an evade police incident ensued," police said.

"The vehicle came to a stop on Great Northern Highway in Bindi Bindi following the successful deployment of a tyre deflation device.

"The 33-year-old man, who was acting aggressively, challenged police and a Taser was deployed."

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The man was taken into custody.

The man, from Byford, has since been charged with one count of murder.

He will appear before the Armadale Magistrates Court tomorrow.

Support is available from the National Sexual Assault, Domestic Family Violence Counselling Service at 1800RESPECT (1800 737 732).