Two people are feared dead and another is fighting for life after a bus crash on a major highway in Queensland.

Emergency services were called to the Bruce Highway near Rangemore Road at Gumlu, about 135 kilometres south of Townsville, before 4pm today after reports the large coach had rolled.

Queensland Ambulance paramedics were assessing 30 people at the scene.

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Ten people have been flown to Ayr Hospital, while another four have been taken to Bowen for treatment.

The condition of the other passengers had not been confirmed.

Almost a dozen ambulance crews were at the scene.

The road is closed to all traffic in both directions and motorists are being told to avoid the area.

The crash happened near the scene of a 2024 crash involving a Greyhound bus.

In that crash, three women aged 56, 33 and 21 died, while several other bus passengers were injured.

More to come.