GENEVA – More than 30 million inoculations for COVID-19 have already been administered in the 47 mostly high-income countries according to the World Health Organization (WHO). But, the global vaccine rollout has exposed glaring inequalities in access to this life-saving tool.

More than 2,800 scientists from 130 countries gathered on Jan. 15 in a virtual forum hosted by the WHO, to identify knowledge gaps and set research priorities for vaccines against COVID-19.

Experts discussed the safety and efficacy of existing vaccines and new candidates, ways to optimize limited supply, and the need for additional safety studies.

“The development and approval of several safe and effective vaccines less than a year after this virus was isolated and sequenced is an astounding scientific accomplishment,” Tedros Adhanom Ghebreyesus, WHO Director-General, said in his opening remarks. “The approval of the first few vaccines does not mean the job is done. Far from it. More vaccines are in the pipeline, which must be evaluated to ensure we have enough doses to vaccinate everyone.”

They agreed on the need for critical research on administering vaccines in different target populations, as well as on vaccination delivery strategies and schedules. This includes trials, modelling and observational studies, all of which would help to inform policy.

They discussed the impact of emerging SARS-CoV-2 variants on the efficacy of vaccines, the impact of vaccines on the transmission of infection, and the need to develop the next generation of vaccine platforms.

“The world needs multiple vaccines that work in different populations to meet global demand and end the covid-19 outbreak. Ideally, those will be single-dose vaccines that do not require a cold chain, could be delivered without a needle and syringe and are amenable to large-scale manufacture,” Mike Levine, Director of the Centre for Vaccine Development at the University of Maryland said.

The meeting concluded with an agreement to establish a WHO-hosted platform for global sharing and coordination of emerging vaccine research information on efficacy and safety. The forum would enable scientists to share and discuss unpublished and published data and research protocols to further our collective understanding of SARS-CoV-2 vaccines.

“The WHO will regularly convene experts from around the world, promote collaborative research, provide standard protocols and develop a platform for sharing the latest knowledge in the field,” Soumya Swaminathan, WHO Chief Scientist said.

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